Nicotinamide Mononucleotide (NMN)
NMN is a direct precursor to NAD⁺, a coenzyme essential for cellular energy metabolism and mitochondrial function. Clinical studies have demonstrated that NMN supplementation effectively increases blood NAD⁺ levels. For instance, a randomized, double-blind, placebo-controlled trial involving 80 healthy middle-aged adults found that daily oral doses of 300 mg, 600 mg, or 900 mg NMN over 60 days significantly elevated blood NAD⁺ concentrations and improved physical performance without adverse effects . Another study confirmed the safety of 1250 mg/day NMN over four weeks, with no reported toxicity or side effects .
Trimethylglycine (TMG)
Also known as betaine, TMG serves as a methyl donor in the remethylation of homocysteine to methionine, supporting methylation processes vital for DNA synthesis and repair. While specific clinical trials on TMG's role in methylation are limited, its biochemical function as a methyl donor is well-established in scientific literature.
Resveratrol
Resveratrol is a polyphenolic compound known to activate sirtuin enzymes, particularly SIRT1, which are involved in cellular aging, inflammation, and metabolic regulation. Research indicates that resveratrol enhances SIRT1 activity, contributing to improved endothelial function and cardiovascular health . Its antioxidant properties also play a role in protecting cells from oxidative stress.
Pterostilbene
A natural analog of resveratrol, pterostilbene exhibits superior bioavailability and similar sirtuin-activating properties. Clinical studies have shown that pterostilbene supplementation can reduce blood pressure and improve lipid profiles in adults . Additionally, it has been observed to activate SIRT1, thereby promoting vascular endothelial health and delaying cellular senescence .
Methylcobalamin (Methyl B12)
Methyl B12 is the bioactive form of vitamin B12, essential for neurological function, DNA synthesis, and methylation reactions. Deficiency in B12 can lead to anemia and neurological disorders. Supplementation with methyl B12 has been shown to improve cognitive function and reduce homocysteine levels, thereby supporting cardiovascular health.
Proprietary Absorption and Utilization Blend
Our unique blend is designed to enhance the bioavailability and efficacy of the active ingredients. While specific components are proprietary, the formulation aims to optimize the delivery and utilization of NMN and synergistic compounds, ensuring maximum therapeutic benefit.
This comprehensive formulation leverages clinically supported ingredients to promote cellular energy, support healthy aging, and enhance overall well-being.
