Clinical Evidence
Lion’s Mane (Hericium erinaceus) – 200 mg (8:1 Fruiting Body Extract)
Lion’s Mane is renowned for its neuroprotective properties. Studies suggest it may support cognitive function and nerve regeneration, potentially aiding in memory and focus.
Cordyceps (Cordyceps militaris) – 200 mg (8:1 Fruiting Body Extract)
Cordyceps has been associated with enhanced energy and endurance. Research indicates that Cordyceps supplementation can improve exercise performance by increasing ATP production, the primary energy carrier in cells. Additionally, Cordyceps has been shown to possess anti-inflammatory properties, which may contribute to improved physical performance and recovery.
Reishi (Ganoderma lucidum) – 200 mg (8:1 Fruiting Body Extract)
Reishi is renowned for its immune-modulating properties. A study on rats revealed that Reishi supplementation enhanced Immunoglobulin A (IgA) secretion and increased the expression of alpha-defensins in the small intestine, suggesting a strengthened mucosal immune response.
PubMed
Chaga (Inonotus obliquus) – 200 mg (8:1 Fruiting Body Extract)
Chaga mushrooms are rich in antioxidants, particularly polyphenols and melanin. These compounds help combat oxidative stress, which is linked to aging and various chronic diseases. While specific clinical studies on Chaga are limited, its high antioxidant content supports its traditional use in promoting overall health.
Maitake (Grifola frondosa) – 200 mg (8:1 Fruiting Body Extract)
Maitake mushrooms contain beta-glucans known to stimulate the immune system. Research indicates that Maitake supplementation can enhance immune responses, including increased activity of natural killer (NK) cells and macrophages, which are vital for defending against pathogens.
Annals of Translational Medicine
Turkey Tail (Trametes versicolor) – 200 mg (8:1 Fruiting Body Extract)
Turkey Tail is rich in polysaccharopeptides like PSK and PSP, which have been studied for their immune-enhancing effects. These compounds may support immune function by promoting the activity of various immune cells and modulating cytokine production.
Shiitake (Lentinula edodes) – 200 mg (8:1 Fruiting Body Extract)
Shiitake mushrooms are known for their immune-supportive properties. A study involving healthy adults found that daily consumption of Shiitake mushrooms improved immunity by enhancing T-cell proliferation and increasing secretory IgA levels, which play a crucial role in mucosal immunity.
Ashwagandha (Withania somnifera) – 200 mg (Extract)
Ashwagandha is an adaptogenic herb traditionally used to reduce stress and anxiety. Clinical studies have demonstrated that Ashwagandha supplementation can lower cortisol levels and improve stress resilience. For instance, a randomized controlled trial found that participants taking Ashwagandha experienced significant reductions in perceived stress and serum cortisol levels.
PubMed
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PubMed
Himalayan Shilajit – 200 mg (Extract)
Shilajit is a mineral-rich substance traditionally used to enhance vitality and energy. It contains fulvic acid and other compounds that may support mitochondrial function and energy production. Some studies suggest that Shilajit supplementation can improve physical performance and reduce fatigue.