NAD+

Clarity Nootropic Nasal Spray: Ingredients, Effects and Use

A plain spray bottle with light rays around it on a dark green background, the cover image for our guide to the Clarity nootropic nasal spray.

Meet Clarity Nasal Spray From Synchronicity Health

Clarity Nasal Spray is our nootropic nasal spray for focus and mental energy. Each serving (one spray in each nostril) of the Maximum strength combines four ingredients that work on two sides of how the brain performs: NAD+ 150 mg for cellular energy, Alpha GPC 20 mg and Huperzine A 200 mcg for acetylcholine, the messenger behind attention and learning, and vitamin B12 500 mcg for normal energy metabolism and nerve function.

This guide covers exactly what is in Clarity Nasal Spray, how each ingredient works, what the research shows, how to use it, how it compares with Clarity Capsules, and who should check with a clinician first.

Clarity Nasal Spray

Featured in this article

Clarity Nasal Spray

NAD+, Alpha GPC, Huperzine A and vitamin B12 in one nasal spray for focus.

Shop Clarity Nasal Spray

Third-party tested ingredients. Vegan, non-GMO, made in the USA.

Key Takeaways

  • Four ingredients per serving (Maximum strength): NAD+ 150 mg, Alpha GPC 20 mg, Huperzine A 200 mcg and vitamin B12 500 mcg, in alkaline water, and nothing else. Regular and Extra strengths hold smaller amounts of the same four: NAD+ 50 or 100 mg, Alpha GPC 10 or 15 mg, Huperzine A 100 or 150 mcg and vitamin B12 200 or 350 mcg.
  • Two jobs: NAD+ and B12 support cellular energy; Alpha GPC and Huperzine A support acetylcholine, one by supplying its raw material and one by slowing its breakdown.
  • Not a stimulant: there is no caffeine in Clarity Nasal Spray.
  • What the research shows: each ingredient has human research, mostly in oral forms, tied to its role in cellular energy, acetylcholine or normal nerve function.
  • Use it as the product page directs: one spray in each nostril, once daily, head tilted back slightly, then wait at least 60 seconds before blowing your nose.

What Is in Clarity Nasal Spray?

Here is the full active formula per serving of two sprays, straight from the label. Each bottle holds 30 servings.

Ingredient

Per serving (Maximum)

What it does

Learn more

NAD+ (nicotinamide adenine dinucleotide)

150 mg

Coenzyme for cellular energy and repair

NAD+ guide

Alpha GPC

20 mg

Supplies choline, the raw material for acetylcholine

Alpha GPC guide

Huperzine A

200 mcg

Slows the enzyme that breaks acetylcholine down

Huperzine A guide

Vitamin B12

500 mcg

Supports normal energy metabolism and nerve function

Vitamin B12 guide

Clarity Nasal Spray contains no caffeine and no other stimulants.

How Each Ingredient Works

NAD+: Energy at the Cellular Level

NAD+ is a coenzyme found in every cell. Mitochondria need it to turn food into ATP, the energy currency that powers everything from muscle contraction to the firing of neurons, and NAD+-dependent enzymes such as sirtuins and PARPs help with DNA repair and stress responses. NAD+ levels decline with age, which is why it is a popular focus of healthy aging research. The brain is one of the most energy-hungry organs in the body, which is the reason NAD+ sits at the center of a focus formula.

Most human NAD+ research has used oral precursors such as NMN or IV infusions. In Clarity Nasal Spray, we describe NAD+ as supporting cellular energy, the role it plays in every cell, rather than promising a specific result. For more on the delivery question, see our NAD+ nasal spray guide.

Alpha GPC: Raw Material for Acetylcholine

Alpha GPC is a well absorbed source of choline, which neurons use to build acetylcholine, the messenger most closely tied to attention and learning. Human studies of alpha GPC have used 250 to 1,000 mg by mouth. The 20 mg in the Maximum strength of Clarity Nasal Spray is a much smaller supporting amount, included to keep the acetylcholine system supplied alongside huperzine A rather than to match those study doses.

Huperzine A: Keeping Acetylcholine Available

Huperzine A comes from a club moss and gently slows acetylcholinesterase, the enzyme that breaks acetylcholine down, so more of it stays available at the synapse. Studies have mostly used 100 to 400 mcg a day by mouth; Clarity Nasal Spray provides 100 to 200 mcg per serving, depending on strength. Because huperzine A acts on the nervous system, it is the ingredient that most calls for sticking to the label and checking with a clinician if you take medication.

Vitamin B12: Energy Metabolism and Nerve Function

Vitamin B12 helps the body release energy from food and is needed to maintain healthy nerve cells and red blood cells. Low B12 is common in people who eat little or no animal food and in older adults. Clarity Nasal Spray provides 200 to 500 mcg per serving, depending on strength. You can read more about this vitamin in our B12 ingredient guide.

How They Work Together

The formula is built around two ideas. First, the brain needs energy, which NAD+ and B12 support. Second, attention depends on acetylcholine: Alpha GPC supplies the raw material to make it, and Huperzine A slows its breakdown. That pairing draws on the research behind each ingredient: NAD+ as a coenzyme for cellular energy, B12 for normal energy metabolism, and Alpha GPC and Huperzine A for acetylcholine.

For how NAD+ and huperzine A fit together in a focus routine, see NAD+ nasal spray and huperzine A for focus.

Why a Nasal Spray?

A nasal spray is absorbed through the thin lining of the nose instead of being swallowed. That makes it portable, easy to use without water, and simple to dose one serving at a time. Most human research on NAD+, Alpha GPC, Huperzine A and B12 has used oral or injected forms, so we do not claim that the spray works faster or better than capsules. If you would rather take a capsule, Clarity Capsules are our oral focus formula. For a general comparison of the two formats, see nasal sprays vs capsules.

Clarity Nasal Spray vs Clarity Capsules

The two Clarity products share one ingredient, huperzine A, but are otherwise built differently.

Feature

Clarity Nasal Spray

Clarity Capsules

Format

Nasal spray, 2 sprays per serving

Capsules, 2 per serving

Main ingredients

Maximum strength: NAD+ 150 mg, Alpha GPC 20 mg, Huperzine A 200 mcg, vitamin B12 500 mcg

Lion's mane 250 mg, epimedium 200 mg, maca 200 mg, bacopa 200 mg, rhodiola 150 mg, Huperzine A 200 mcg

Approach

Cellular energy plus acetylcholine support

Botanical and mushroom extracts taken daily

Directions

One spray in each nostril, once daily

Two capsules daily, in the morning

Caffeine

None

None

Both contain huperzine A (200 mcg per serving in the capsules and 100 to 200 mcg in the spray), so avoid using them together, or adding another huperzine product, unless your clinician agrees. The capsules include bacopa, lion's mane and rhodiola, which are studied over weeks of daily use.

How to Use Clarity Nasal Spray

Always follow the directions on your label. The product page directions are:

  1. Once daily, dispense one spray in each nostril while gently inhaling through your nose.
  2. Tilt your head back slightly.
  3. Leave it for at least 60 seconds for absorption before blowing your nose.

One serving is two sprays, one in each nostril, used once daily, and each bottle holds 30 servings. Many people use it before focused work. Because it supports alertness, avoid using it close to bedtime until you know how it affects you. For more on NAD+ nasal sprays in general, see our NAD+ nasal spray dosage guide and the Clarity Nasal Spray FAQ.

Stacking

Our Focus Stack pairs Clarity Nasal Spray with NAC Nasal Spray and Theanine Nasal Spray, which supports relaxation without sedation. Add one product at a time so you can tell what each one contributes, and keep the basics in place: sleep, movement, food and managing stress do more for focus than any supplement. For how alpha GPC and L-theanine compare and pair, see our guide to alpha GPC and L-theanine.

Safety and Side Effects

Clarity Nasal Spray is generally well tolerated when used as directed. The most common reactions to any nasal spray are local and short-lived: a brief sting, sneezing, or a dry feeling in the nose. Stop using it if you notice persistent irritation or nosebleeds.

The individual ingredients have their own reported side effects when taken by mouth, including nausea, headache and dizziness, and huperzine A may slow the heart rate in some people. Speak with a qualified healthcare professional before using Clarity Nasal Spray if you:

  • Are pregnant or nursing
  • Take any prescription medication, especially drugs that act on acetylcholine, such as those prescribed for memory, bladder control or glaucoma
  • Have a heart rhythm condition, a seizure disorder, asthma or a stomach ulcer
  • Already take another product that contains huperzine A

Clarity contains alpha GPC; our guide to alpha GPC side effects covers what studies found at the much larger oral amounts used in research.

Who Clarity Nasal Spray Is For

  • Professionals and students who want focus support for long stretches of deep work without relying on more caffeine.
  • People building an NAD+ routine who want a spray that also covers acetylcholine.
  • Anyone who prefers not to swallow capsules or wants a portable option for travel.

If you are not sure whether it fits, the cognitive health guide and our guide to stimulant-free energy and focus cover the wider picture.

Clarity Nasal Spray is part of our best-selling collection, alongside the NAD+ and glutathione nasal sprays.

Sources

  • Verdin E. NAD+ in aging, metabolism, and neurodegeneration. Science. 2015. PubMed 26785480
  • NIH Office of Dietary Supplements. Choline: Fact Sheet for Health Professionals. ods.od.nih.gov
  • Wang R, Yan H, Tang XC. Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine. Acta Pharmacol Sin. 2006. PubMed 16364207
  • NIH Office of Dietary Supplements. Vitamin B12: Fact Sheet for Health Professionals. ods.od.nih.gov

FAQs

What is in Clarity Nasal Spray?
Each two-spray serving of the Maximum strength contains NAD+ 150 mg, Alpha GPC 20 mg, Huperzine A 200 mcg and vitamin B12 500 mcg, in alkaline water, and nothing else. Regular and Extra strengths hold smaller amounts of the same four: NAD+ 50 or 100 mg, Alpha GPC 10 or 15 mg, Huperzine A 100 or 150 mcg and vitamin B12 200 or 350 mcg. It contains no caffeine.

Is Clarity Nasal Spray a stimulant?
No. It supports cellular energy and the acetylcholine system rather than stimulating the nervous system the way caffeine does.

How do I use it?
Once daily, dispense one spray in each nostril while gently inhaling, tilt your head back slightly, and wait at least 60 seconds before blowing your nose. Follow the directions on your label.

Can I use Clarity Nasal Spray with Clarity Capsules?
Both contain huperzine A, so avoid using them together unless your clinician agrees.

What does research on the ingredients in Clarity Nasal Spray show?
Each ingredient has human research, mostly in oral forms: NAD+ as a coenzyme for cellular energy, Alpha GPC and Huperzine A for acetylcholine, and vitamin B12 for normal energy metabolism and nerve function. Our ingredient guides cover it in more detail.

Clarity Nasal Spray

Featured in this article

Clarity Nasal Spray

NAD+, Alpha GPC, Huperzine A and vitamin B12 in one nasal spray for focus.

Shop Clarity Nasal Spray

Third-party tested ingredients. Vegan, non-GMO, made in the USA.

Final Thoughts

Clarity Nasal Spray brings NAD+, Alpha GPC, Huperzine A and vitamin B12 together in one portable spray, aimed at the two things focus depends on: energy and acetylcholine. Use it as directed, give the basics their due, and talk with your clinician if you take medication. For the science behind each ingredient, start with the NAD+, Alpha GPC and Huperzine A guides.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This article is for general education and is not medical advice.

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About the author

Founder and CEO, Synchronicity Health

George Given is the founder and CEO of Synchronicity Health, which he started in 2022. He has worked in supplement formulation and manufacturing since 2017 and has led product formulation as a head formulator since 2019. At Synchronicity he builds every formula around a short, fully disclosed label that lists the amount of every ingredient, and he works only with third-party tested ingredients. Under his direction, most of Synchronicity's sprays were rebuilt around a single active ingredient in alkaline water, and its capsules use vegan capsules with no fillers, no flow agents and no magnesium stearate. He writes about the research behind the ingredients Synchronicity uses, with a focus on what the studies actually measured.

More about George · George on LinkedIn · How we research and check our guides